大奖娱乐官网首页:Anti-DACT3/FITC抗体 Anti-DACT3/FITC

产品价格: < 面议
产品型号:Anti-DACT3/FITC
 牌:科研抗体
公司名称:上海钰博生物科技有限公司
  地:上海松江
发布时间:2018-09-14
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Anti-DACT3/FITC抗体和抗原之间的结合具有高度的特异性,免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来,以此作为抗原或半抗原,Anti-DACT3/FITC抗体通过免疫动物后获得特异性的抗体,再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的,因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来,以其达到对组织或细胞中的未知抗原进行定性,定位或定量的研究。

产品详细信息

Anti-DACT3/FITC抗体

品编号YB11837R-FITC

英文名称Anti-DACT3/FITC

中文名称FITC标记的Dapper3蛋白抗体

别    名Antagonist of beta-catenin Dapper homolog 3; Arginine rich region 1; Arginine rich region 1 protein; Arginine-rich region 1 protein; Dact3 antibody; DACT3_HUMAN; Dapper antagonist of beta catenin 3; Dapper antagonist of beta catenin homolog 3 (Xenopus laevis); Dapper homolog 3; Dapper3; Dpr3 antibodyRRR1; RRR1; Thymus expressed gene 3 like.

Anti-DACT3/FITC抗体

说 明 书100ul  

研究领域肿瘤  干细胞  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应 Human, Mouse, Rat, Pig, Cow, Sheep,

产品应用ICC=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量65kDa

Anti-DACT3/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human DACT3

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-DACT3/FITC抗体

产品介绍background:

Dapper3 is a 629 amino acid protein and mammalian homolog of the Xenopus laevis protein dapper. As a member of the dapper family, Dapper3 plays a role in postnatal brain development and contains a C-terminal PDZ-binding motif that facilitates interaction with the PDZ domains of DSH (Dishevelled) family proteins. As the predominant dapper family member found in ***** brain, Dapper 3 localizes to hippocampus, Purkinje cell layer and every layer of the dorsal forebrain and cerebral cortex and is also found in the developing murine central nervous system. Dapper3 is also expressed in uterus, ventral somites, branchial arch mesenchyme, aortic sac, aortic arches, limb bud mesenchyme and craniofacical mesenchyme. Mapping to human chromosome 19q13.32, Dapper3 has been identified as a negative regulator of Wnt/beta-catenin signaling in colorectal cancer.


Function:

May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins.


Subunit:

Can form homodimers and heterodimers with DACT1 or DACT3. Interacts with CSNK1D, PKA catalytic subunit, PKC-type kinase, DVL1, DVL3, VANGL1, VANGL2 and CTNND1 (By similarity). Interacts with DVL2.


Anti-DACT3/FITC抗体Tissue Specificity:



Post-translational modifications:



Similarity:

Belongs to the dapper family.


Database links:

UniProtKB/Swiss-Prot: Q96B18.2


Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.



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